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organic reactions and mechanisms

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PROTECTION OF AMINE: di-tert-butyl dicarbonate [Boc anhydride (Boc)2O]: Boc protection
Amines are reactive functional groups that can participate in a variety of chemical reactions. While this reactivity can be advantageous in some reactions, it can also be problematic in others. For example,...
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REDUCTIVE AMINATION: USING SODIUM TRIACETOXYBOROHYDRIDE AND SODIUM CYANOBOROHYDRIDE
Amines are incredibly versatile and important compounds in organic chemistry. They play crucial roles in both natural and synthetic chemistry, and their unique properties make them useful in a wide range...
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VILSMEIER REAGENT: Vilsmeier-Haack formylation reaction
The introduction of formyl (-CHO) group into electron -rich aromatic compounds using a Vilsmeier reagent is known as the Vilsmeier-Haack formylation reaction. The Vilsmeier reagent is prepared from any...
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SYNTHESIS OF ETHER
ACID–CATALYZED DEHYDRATION OF ALCOHOLS Diethyl ether and several other symmetrical ethers are prepared by the acid-catalyzed dehydration of alcohols. The yields are usually higher for symmetrical...
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DIAZONIUM SALTS AND SYNTHETIC APPLICATIONS:
Diazonium salt is a versatile and important class of compounds in organic chemistry. It has played a significant role in the development of the chemical industry, particularly in the production of dyes...
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ALLELOPATHY AND ALLELOCHEMICALS: CHEMICAL STRUCTURES OF COMMON ALLELOCHEMICALS
Allelopathy is a biological phenomenon in which one plant produces biochemicals that affect the growth, survival, or reproduction of other plants. Some plants can have a positive allelopathic effect on...
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NUCLEOPHILIC DEOXYGENATION OF ALCOHOLS: USING LITHIUM ALUMINUM HYDRIDES OR BOROHYDRIDES
In the previous article we have discussed about the deoxygenation of alcohols, which is a common synthetic procedure. There are two main methods for deoxygenation: radical and nucleophilic. The radical...
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REDUCTION OF ALCOHOL: DEOXYGENATION: BARTON-McCOMBIE RADICAL DEOXYGENATION
Alcohols are a ubiquitous and versatile class of compounds in organic chemistry. They are present in natural products, pharmaceuticals, etc., and are ubiquitous synthetic handles for a multitude of organic...
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OXIDATION OF ALCOHOLS: PART III: DMP AND TEMPO
DESS-MARTIN PERIODINANE (DMP): In 1983, D. B. Dess and J. C. Martin reported DMP (Dess-Martin Periodinane). This periodinane, which is far more soluble in organic solvents than IBX (2-Iodoxybenzoic acid),...
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OXIDATION OF ALCOHOLS: PART II: DMSO AS AN OXIDANT
Parikh-Doering Oxidation: The oxidation of primary and secondary alcohol to aldehyde and ketone respectively using sulfur trioxide in the form of its pyridine complex (SO3.C5H5N) and dimethyl sulfoxide...
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