organic reactions and mechanisms

Dieckmann condensation is a type of organic reaction that involves the intramolecular condensation of diesters with base to form cyclic β-ketoesters. The reaction is named after the German chemist Walter...

The Hofmann reaction (also called Hofmann degradation or Hofmann rearrangement) was previously reported in 1881 by the German chemist August Wilhelm Von Hofmann (1818–1892) and is the conversion of carboxamides...

Lead tetraacetate [Pb(OAc)4] is a commercially available crystalline solid used as a solution in acetic acid or benzene for the oxidation of organic compounds. Although lead tetraacetate may be employed...

If you are looking for a way to convert secondary alcohols to ketones without affecting other sensitive functional groups, you might want to consider the Oppenauer oxidation. This is a classic organic...

The reaction is named after Russian chemist Nikolay Prilezhaev, who first reported the reaction in 1909. The Prilezhaev reaction, also known as the Prilezhaev epoxidation, is a chemical reaction that involves...

The Baeyer Villiger oxidation is an organic reaction that converts a ketone into an ester or a cyclic ketone into a lactone by breaking a carbon-carbon bond and inserting an oxygen atom. The reaction requires...

The Reimer Tiemann reaction was first reported by Karl Reimer in 1876, who obtained salicylaldehyde from phenol and chloroform in an alkaline solution. He also observed that other phenols gave similar...

OXIDATION OF ALCOHOL: Potassium permanganate (KMnO4) is a very strong oxidant able to oxidize many functional groups like alcohols, aldehydes, alkenes, etc. Under controlled conditions, KMnO4 oxidizes...

Manganese dioxide (MnO2) is an oxidizing reagent for the selective oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones. This reaction is widely used in organic synthesis...

In the field of medicinal/organic chemistry, the amide coupling reaction has become very popular in recent years. The amide bond is a fundamental component of proteins and is formed by condensing a carboxylic...