organic reactions and mechanisms

The reduction of aldehydes and ketones to the primary and secondary alcohols represents important synthetic transformations. One of the most chemoselective and mild reactions for these types of reductions...

The Diels-Alder reaction is a chemical process between a conjugated diene and an alkene, also known as a dienophile. This reaction results in the formation of unsaturated six-membered rings (cyclohexene)....

The thermal [3,3]-sigmatropic rearrangement of 1,5-dienes to the regioisomeric 1,5-dienes is called the Cope Rearrangement. The main product is the thermodynamically more stable regioisomer. The reaction...

The Wittig reaction is perhaps the most commonly used method for the synthesis of alkenes. The reaction occurs between a carbonyl compound (aldehyde or ketone) and a phosphorus ylide to give an alkene...

Thermal [3,3]-sigmatropic rearrangement of allyl vinyl ether (or allyl phenyl ether) to the corresponding unsaturated carbonyl compounds are called the Claisen rearrangement. It was first reported by Ludwig...

The 1,4-reduction of aromatic rings to the corresponding unconjugated cyclohexadiene by alkali metals (Li, Na, K) dissolved in liquid ammonia in the presence of an alcohol is called the Birch reduction....

The rearrangement of ketoximes to the corresponding amide is known as the Beckmann rearrangement. It accomplishes in one stroke both the cleavage of a carbon-carbon bond and the formation of a carbon-nitrogen...

The generation of a carbocation followed by the [1,2]-shift of an adjacent carbon-carbon bond to generate a new carbocation is known as the Wagner–Meerwein rearrangement. It is named after the German...

The Pinacol-pinacolone rearrangement is a notable organic reaction that involves the rearrangement of a pinacol (1,2-diol) to form a pinacolone (ketone/aldehyde) compound. This reaction was first discovered...

The thermal decomposition of acyl azides to the corresponding isocyanates is known as the Curtius rearrangement. This rearrangement is named after the German chemist Theodor Curtius, who first observed...