PINACOL – PINACOLONE REARRANGEMENT
The Pinacol-pinacolone rearrangement is a notable organic reaction that involves the rearrangement of a pinacol (1,2-diol) to form a pinacolone (ketone/aldehyde) compound. This reaction was first discovered by Wilhelm Rudolph Fittig in 1860. This rearrangement involves a 1,2-shift of substituents with concomitant formation of a C-H or C-C bond α to a carbonyl group. The …